Summary: Analysis of The Cancer Genome Atlas and other published data of head and neck squamous cell carcinoma (HNSCC) reveals somatic alterations of the Hippo-YAP pathway in approximately 50% of HNSCC.Better strategies to target the YAP1 transcriptional complex are sought.Here, we show that FAT1, an upstream inhibitor of YAP1, is mutated either by
Marine protected areas (MPAs) are valuable tools for marine conservation that aim to limit human impacts on marine systems and protect valuable species or habitats.However, as species distributions shift due to ocean warming, acidification, and oxygen depletion from climate change, the areas originally designated under MPAs may bear little resembla
This paper examined the application of regression model in the forecast of click here travel demand in cities using Akure as a reference point.The aim is to examine the effectiveness of regression model in predicting travel demand in any urban environment.The data used for this study was derived from a larger study of Akure and the data were collec
This experiment investigated the effect of number of visual demonstrations on the acquisition of My Mom Dad Is Well Trained Funny Cartoon Dog Gift For Dog Lover Personalized Shirt discreet motor skill.Seventy-four college students of both sex participated in this study.The participants observed a visual model twice or ten times.In the acquisition p
Background & Aims: Epidemiological and animal studies have indicated an inverse correlation between the rising prevalence of obesity and metabolic syndrome and exposure to helminths.Whether helminth-induced immune response contributes to microbiota remodeling in obesity remains unknown.The aim of this study is to explore the immune-regulatory r